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Shigenaga, Akira

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Facile Preparation of Peptides with C-Terminal N-Alkylamide via Radical-Initiated Dethiocarboxylation
Author Shimizu, Tatsuhiko/ Miyajima, Rin/ Naruse, Naoto/ Yamaoka, Kosuke/ Aihara, Keisuke/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Chemical and Pharmaceutical Bulletin
Volume 64
Issue 4
Published Date 2016-04-01
departments Pharmaceutical Sciences
An N-sulfanylethylanilide-based traceable linker for enrichment and selective labelling of target proteins
Author Morisaki, Takuya/ Denda, Masaya/ Yamamoto, Jun/ Tsuji, Daisuke/ Inokuma, Tsubasa/ Itoh, Kohji/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Chemical Communications
Volume 52
Issue 42
Published Date 2016-04-26
departments Pharmaceutical Sciences
Facile synthesis of C-terminal peptide thioacids under mild conditions from N-sulfanylethylanilide peptides
Author Shimizu, Tatsuhiko/ Miyajima, Rin/ Sato, Kohei/ Sakamoto, Ken/ Naruse, Naoto/ Kita, Miku/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Tetrahedron
Volume 72
Issue 7
Published Date 2015-12-29
departments Pharmaceutical Sciences
Development of a Reduction‐Responsive Amino Acid that Induces Peptide Bond Cleavage in Hypoxic Cells
Author Shigenaga, Akira/ Ogura, Keiji/ Hirakawa, Hiroko/ Yamamoto, Jun/ Ebisuno, Koji/ Miyamoto, Licht/ Ishizawa, Keisuke/ Tsuchiya, Koichiro/ Otaka, Akira/
Content Type Journal Article
Journal Title ChemBioChem
Volume 13
Issue 7
Published Date 2012-04-13
departments Pharmaceutical Sciences Medical Sciences
Development of a traceable linker containing a thiol-responsive amino acid for the enrichment and selective labelling of target proteins
Author Yamamoto, Jun/ Denda, Masaya/ Maeda, Nami/ Kita, Miku/ Komiya, Chiaki/ Tanaka, Tomohiro/ Nomura, Wataru/ Tamamura, Hirokazu/ Sato, Youichi/ Yamauchi, Aiko/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Organic & Biomolecular Chemistry
Volume 12
Issue 23
Published Date 2014-04-17
departments Pharmaceutical Sciences
Development of caged non-hydrolyzable phosphoamino acids and application to photo-control of binding affinity of phosphopeptide mimetic to phosphopeptide-recognizing protein
Author Ebisuno, Koji/ Denda, Masaya/ Ogura, Keiji/ Inokuma, Tsubasa/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Bioorganic & Medicinal Chemistry
Volume 22
Issue 11
Published Date 2014-04-13
departments Pharmaceutical Sciences
Design and synthesis of a hydrogen peroxide-responsive amino acid that induces peptide bond cleavage after exposure to hydrogen peroxide
Author Kita, Miku/ Yamamoto, Jun/ Morisaki, Takuya/ Komiya, Chiaki/ Inokuma, Tsubasa/ Miyamoto, Licht/ Tsuchiya, Koichiro/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Tetrahedron Letters
Volume 56
Issue 28
Published Date 2015-05-21
departments Pharmaceutical Sciences
Development of a fluoride-responsive amide bond cleavage device that is potentially applicable to a traceable linker
Author Yamamoto, Jun/ Maeda, Nami/ Komiya, Chiaki/ Tanaka, Tomohiro/ Denda, Masaya/ Ebisuno, Koji/ Nomura, Wataru/ Tamamura, Hirokazu/ Sato, Youichi/ Yamauchi, Aiko/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Tetrahedron
Volume 70
Issue 34
Published Date 2014-06-06
departments Pharmaceutical Sciences
Design and synthesis of caged ceramide : UV-responsive ceramide releasing system based on UV-induced amide bond cleavage followed by O–N acyl transfer
Author Shigenaga, Akira/ Hirakawa, Hiroko/ Yamamoto, Jun/ Ogura, Keiji/ Denda, Masaya/ Yamaguchi, Keiko/ Tsuji, Daisuke/ Itoh, Kohji/ Otaka, Akira/
Content Type Journal Article
Journal Title Tetrahedron
Volume 67
Issue 22
Published Date 2011-04-20
departments Pharmaceutical Sciences
Development of UV-responsive catch-and-release system of a cysteine protease model peptide
Author Shigenaga, Akira/ Morishita, Ko/ Yamaguchi, Keiko/ Ding, Hao/ Ebisuno, Koji/ Sato, Kohei/ Yamamoto, Jun/ Akaji, Kenichi/ Otaka, Akira/
Content Type Journal Article
Journal Title Tetrahedron
Volume 67
Issue 46
Published Date 2011-09-21
departments Pharmaceutical Sciences
Enantioselective synthesis of stimulus-responsive amino acid via asymmetric α-amination of aldehyde
Author Shigenaga, Akira/ Yamamoto, Jun/ Nishioka, Naomi/ Otaka, Akira/
Content Type Journal Article
Journal Title Tetrahedron
Volume 66
Issue 37
Published Date 2010-07-21
departments Pharmaceutical Sciences
Development and photo-responsive peptide bond cleavage reaction of two-photon near-infrared excitation-responsive peptide
Author Shigenaga, Akira/ Yamamoto, Jun/ Sumikawa, Yoshitake/ Furuta, Toshiaki/ Otaka, Akira/
Content Type Journal Article
Journal Title Tetrahedron Letters
Volume 51
Issue 21
Published Date 2010-03-23
departments Pharmaceutical Sciences
FRET-based assay of the processing reaction kinetics of stimulus-responsive peptides : influence of amino acid sequence on reaction kinetics
Author Shigenaga, Akira/ Yamamoto, Jun/ Hirakawa, Hiroko/ Yamaguchi, Keiko/ Otaka, Akira/
Content Type Journal Article
Journal Title Tetrahedron
Volume 65
Issue 11
Published Date 2009-01-20
departments Pharmaceutical Sciences
Development of thiol-responsive amide bond cleavage device and its application for peptide nucleic acid-based DNA releasing system
Author Shigenaga, Akira/ Yamamoto, Jun/ Hirakawa, Hiroko/ Ogura, Keiji/ Maeda, Nami/ Morishita, Ko/ Otaka, Akira/
Content Type Journal Article
Journal Title Tetrahedron Letters
Volume 51
Issue 18
Published Date 2010-03-03
departments Pharmaceutical Sciences
Synthesis of a Stimulus-responsive Processing Device and Its Application to a Nucleocytoplasmic Shuttle Peptide
Author Shigenaga, Akira/ Tsuji, Daisuke/ Nishioka, Naomi/ Tsuda, Shugo/ Itoh, Kohji/ Otaka, Akira/
Content Type Journal Article
Journal Title ChemBioChem
Volume 8
Issue 16
Published Date 2007-09-26
departments Pharmaceutical Sciences
Preparation of Peptide Thioesters from Naturally Occurring Sequences Using Reaction Sequence Consisting of Regioselective S-Cyanylation and Hydrazinolysis
Author Miyajima, Rin/ Tsuda, Yusuke/ Inokuma, Tsubasa/ Shigenaga, Akira/ Imanishi, Miki/ Futaki, Shiroh/ Otaka, Akira/
Content Type Journal Article
Journal Title Biopolymers(Peptide Science)
Volume 106
Issue 4
Published Date 2015-10-26
departments Pharmaceutical Sciences
Development of an intein-inspired amide cleavage chemical device
Author Komiya, Chiaki/ Aihara, Keisuke/ Morishita, Ko/ Ding, Hao/ Inokuma, Tsubasa/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title The Journal of Organic Chemistry
Volume 81
Issue 2
Published Date 2015-12-08
departments Pharmaceutical Sciences
A recyclable hydrophobic anchor-tagged asymmetric amino thiourea catalyst
Author Jichu, Takahisa/ Inokuma, Tsubasa/ Aihara, Keisuke/ Kohiki, Taiki/ Nishida, Kodai/ Shigenaga, Akira/ Yamada, Ken-ichi/ Otaka, Akira/
Content Type Journal Article
Journal Title ChemCatChem
Volume 10
Issue 16
Published Date 2018-07-11
departments Pharmaceutical Sciences
Liquid-Phase Synthesis of Bridged Peptides Using Olefin Metathesis of a Protected Peptide with a Long Aliphatic Chain Anchor
Author Aihara, Keisuke/ Komiya, Chiaki/ Shigenaga, Akira/ Inokuma, Tsubasa/ Takahashi, Daisuke/ Otaka, Akira/
Content Type Journal Article
Journal Title Organic Letters
Volume 17
Issue 3
Published Date 2015-01-28
departments Pharmaceutical Sciences
Resin-Bound Crypto-Thioester for Native Chemical Ligation
Author Naruse, Naoto/ Ohkawachi, Kento/ Inokuma, Tsubasa/ Shigenaga, Akira/ Otaka, Akira/
Content Type Journal Article
Journal Title Organic Letters
Volume 20
Issue 8
Published Date 2018-04-09
departments Pharmaceutical Sciences
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