Aihara, Keisuke The University of Tokushima
Komiya, Chiaki The University of Tokushima
Inokuma, Tsubasa The University of Tokushima Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Takahashi, Daisuke AJINOMOTO Co., Inc.
Otaka, Akira The University of Tokushima Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Bridged peptides including stapled peptides are attractive tools for regulating protein-protein interactions (PPIs). An effective synthetic methodology in a heterogeneous system for the preparation of these peptides using olefin metathesis and hydrogenation of protected peptides with a long aliphatic chain anchor is reported.
This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters, copyright ©American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/ol503718j.
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