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ID 115999
Title Alternative
Treatment for recurrence after esophagectomy
Author
Sohda, Makoto Gunma University
Yoshida, Tomonori Gunma University
Nakazawa, Nobuhiro Gunma University
Ubukata, Yasunari Gunma University
Kuriyama, Kengo Gunma University
Hara, Keigo Gunma University
Sakai, Makoto Gunma University
Sano, Akihiko Gunma University
Yokobori, Takehiko Gunma University
Ogawa, Hiroomi Gunma University
Shirabe, Ken Gunma University
Saeki, Hiroshi Gunma University
Keywords
esophageal cancer
recurrence pattern
esophagectomy
Content Type
Journal Article
Description
Background : With regard to the recurrence of esophageal cancer after surgery, the prognosis has improved with the progress of multimodal perioperative treatment. In this study, the recurrence pattern, treatment method, and prognosis of recurrent cases following esophageal cancer surgery were retrospectively examined. Materials and Methods : Three hundred seven patients with histologically proven squamous cell carcinoma, adenocarcinoma, and others were enrolled in the study. With respect to clinicopathologic factors and recurrence patterns, recurrence risk factors, recurrence period, treatment for recurrence, and prognosis were investigated. Results : Ninety two percent of all recurrent cases were observed within two years after radical esophagectomy. Locoregional recurrence, distant recurrence, and mixed recurrence were observed in 38 (35%), 56 (51%), and 16 (14%) cases, respectively. Patients with lymph node metastasis showed a significantly longer survival in comparison to those with metastasis to other organs (p = 0.0032). When analyzed using the treatment method, patients who underwent surgery (only surgery or additional postoperative chemotherapy) exhibited better survival in comparison to those who underwent other treatments. Discussion : Detailed and strict follow-up within two years are necessary in cases with deeper than muscular invasion, cases with extensive lymph node metastasis, or cases with lymphatic or vascular invasion.
Journal Title
The Journal of Medical Investigation
ISSN
13496867
13431420
NCID
AA11166929
Publisher
Tokushima University Faculty of Medicine
Volume
68
Issue
1-2
Start Page
129
End Page
135
Sort Key
129
Published Date
2021-02
Remark
著者英表記誤記あり (誤)Nobhiro Nakazawa →(正)Nobuhiro Nakazawa
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher