直近一年間の累計
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ID 115999
タイトル別表記
Treatment for recurrence after esophagectomy
著者
Sohda, Makoto Gunma University
Yoshida, Tomonori Gunma University
Nakazawa, Nobuhiro Gunma University
Ubukata, Yasunari Gunma University
Kuriyama, Kengo Gunma University
Hara, Keigo Gunma University
Sakai, Makoto Gunma University
Sano, Akihiko Gunma University
Yokobori, Takehiko Gunma University
Ogawa, Hiroomi Gunma University
Shirabe, Ken Gunma University
Saeki, Hiroshi Gunma University
キーワード
esophageal cancer
recurrence pattern
esophagectomy
資料タイプ
学術雑誌論文
抄録
Background : With regard to the recurrence of esophageal cancer after surgery, the prognosis has improved with the progress of multimodal perioperative treatment. In this study, the recurrence pattern, treatment method, and prognosis of recurrent cases following esophageal cancer surgery were retrospectively examined. Materials and Methods : Three hundred seven patients with histologically proven squamous cell carcinoma, adenocarcinoma, and others were enrolled in the study. With respect to clinicopathologic factors and recurrence patterns, recurrence risk factors, recurrence period, treatment for recurrence, and prognosis were investigated. Results : Ninety two percent of all recurrent cases were observed within two years after radical esophagectomy. Locoregional recurrence, distant recurrence, and mixed recurrence were observed in 38 (35%), 56 (51%), and 16 (14%) cases, respectively. Patients with lymph node metastasis showed a significantly longer survival in comparison to those with metastasis to other organs (p = 0.0032). When analyzed using the treatment method, patients who underwent surgery (only surgery or additional postoperative chemotherapy) exhibited better survival in comparison to those who underwent other treatments. Discussion : Detailed and strict follow-up within two years are necessary in cases with deeper than muscular invasion, cases with extensive lymph node metastasis, or cases with lymphatic or vascular invasion.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA11166929
出版者
Tokushima University Faculty of Medicine
68
1-2
開始ページ
129
終了ページ
135
並び順
129
発行日
2021-02
備考
著者英表記誤記あり (誤)Nobhiro Nakazawa →(正)Nobuhiro Nakazawa
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版