ID 109840
タイトルヨミ
ゾウゲガ サイボウ ノ ブンカ ト サイボウガイ キシツ
タイトル別表記
Role of Extracellular Matrix in Odontoblast Differentiation
著者
岩本, 勉 徳島大学大学院ヘルスバイオサイエンス研究部医療創生科学部門社会環境衛生学講座小児歯科学分野 徳島大学 教育研究者総覧 KAKEN研究者をさがす
キーワード
象牙芽細胞
象牙質
細胞外基質
資料タイプ
学術雑誌論文
抄録
Tooth development is a complex process that includes interactions between oral epithelium-derived dental epithelial cells and neural crest-derived dental mesenchymal cells. In this process, the basement membrane at the epithelial-mesenchymal interface plays important roles in matrix-mediated cell interactions and for trapping growth factors, then dental epithelial and mesenchymal cells differentiate into enamel-forming ameloblasts and dentin-forming odontoblasts, respectively. For enamel and dentin formation, these cells produce large amounts of extracellular matrixes, thus cell-matrix and cell-cell interactions are crucial for both ameloblast and odontoblast differentiation. In this review, we focus on the role of the extracellular matrix in odontoblast differentiation. Dentin and bone are similar in several aspects, such as extracellular matrix composition and genetic diseases, which affect both bone and dentin mineralization, common between them. However, the process of odontoblast differentiation is completely different from that of osteoblast differentiation. For better understanding of tooth development, it is important to elucidate the differences between these cell types.
掲載誌名
四国歯学会雑誌
ISSN
09146091
cat書誌ID
AN10050046
出版者
四国歯学会
26
2
開始ページ
23
終了ページ
28
並び順
23
発行日
2014-02-14
EDB ID
275178
フルテキストファイル
言語
jpn
著者版フラグ
出版社版
部局
歯学系