ID 110051
著者
ツズキ, ヒロミツ Graduate School of Integrated Arts and Sciences, Tokushima University
イノウエ, ショウタ Graduate School of Integrated Arts and Sciences, Tokushima University
コバヤシ, ダイキ Graduate School of Integrated Arts and Sciences, Tokushima University
Uuganbaatar, Gantulga Graduate School of Integrated Arts and Sciences, Tokushima University
金丸, 芳 Faculty of Bioscience and Bioindustry, Tokushima University 徳島大学 教育研究者総覧 KAKEN研究者をさがす
横井川, 久己男 Faculty of Bioscience and Bioindustry, Tokushima University 徳島大学 教育研究者総覧 KAKEN研究者をさがす
小山, 保夫 Faculty of Bioscience and Bioindustry, Tokushima University 徳島大学 教育研究者総覧 KAKEN研究者をさがす
キーワード
Methyl cinnamate
Hydrogen peroxide
Cytotoxicity
Lymphocytes
Oxidative stress
資料タイプ
学術雑誌論文
抄録
Methyl cinnamate (MC) and essential oils containing MC possess beneficial antimicrobial, antifungal, and insecticidal effects, among ohters. Such effects are related to the biocidal action of MC. The antioxidant activity of MC has also been reported elsewhere. It has been suggested that MC may be cytotoxic to cells exposed to oxidative stress. To test this possibility, the effect of MC on rat thymocytes was examined while the cells were subjected to oxidative stress induced by hydrogen peroxide (H2O2). Flow cytometric techniques with appropriate fluorescent probes were used for quantification. MC increased cell vulnerability to oxidative stress via acceleration of the cell death process and/or poteniation of oxidative stress. The use of MC is widespread because of its beneficial actions, and thus further attention should be paid to whether MC is effective under oxidative stress.
掲載誌名
Fundamental Toxicological Sciences
ISSN
2189115X
3
3
開始ページ
121
終了ページ
125
並び順
121
発行日
2016
備考
Copyright © 2016 The Japanese Society of Toxicology
EDB ID
311924
出典
Fundamental Toxicological Sciences (2016) Vol.3 No.3 p.121-125
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
生物資源系