ID 110461
タイトルヨミ
イデンシ シンダン ト ソノ モンダイテン
タイトル別表記
DNA diagnosis : advantages and weak points
著者
伊藤, 道徳 徳島大学医学部小児科学講座
キーワード
DNA diagnosis
advantage
weak point
資料タイプ
学術雑誌論文
抄録
In recent years, many disease-related genes has been found with the development of molecular biological technique and molecular genetical analyses in patients with these diseases have been performed in clinical medicine. DNA diagnosis, diagnosis by detection of the mutation in disease-related genes, has a lot of advantages compared to usual diagnostic method. However, DNA diagnosis still has several weak points in clinical medicine. The first weak point is that we can not diagnose the patient as normal even when no mutation is found by DNA analysis. The second weak point is that functional analysis of the gene product,which is hard in clinical medicine, is necessary to confirm the mutation as the pathogenic mutation when the new mutation is found in the patient. Finally, it is also the problem that the sufficient supporting system for the patients after DNA diagnosis is not established in Japan. Then, it is important that not only advantages but also these weak points are fully considered before DNA diagnosis.
掲載誌名
四国医学雑誌
ISSN
00373699
cat書誌ID
AN00102041
出版者
徳島医学会
56
5
開始ページ
160
終了ページ
164
並び順
160
発行日
2000-10-25
フルテキストファイル
言語
jpn
著者版フラグ
出版社版