ID 111488
著者
Karabasil, Mileva R The University of Tokushima|Belgrade University
Murdiastuti, Kwartarini Gadjah Mada University
Purwanti, Nunuk The University of Tokushima|Gadjah Mada University
Azlina, Ahmad The University of Tokushima
フルジャフ, ジャフラン The University of Tokushima
キーワード
AQP5 mutant
trafficking
salivary gland
資料タイプ
学術雑誌論文
抄録
In the colony of Sprague-Dawley (SD) strain, we found that there were rats expressing a mutant AQP5, which has a point mutation at nt 308 (G308A), leading to a replacement of 103Gly with 103Asp in the 3rd transmembrane domain. The mutant molecule scarcely expressed in the acinar cells, probably because of ineffective trafficking. The mutant molecule, however, showed normal water permeability when assessed by the oocyte system.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA11166929
AA12022913
出版者
Faculty of Medicine Tokushima University
56
Supplement
開始ページ
398
終了ページ
400
並び順
398
発行日
2009-12
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
歯学系
生物資源系