ID 111858
タイトル別表記
A Fundamental Studies on Utilization of Medical Exchange Resins for Acute Poisoning by Paraquat containing Herbicide
著者
田辺, 暁人 徳島大学
田村, 隆教 徳島大学
田辺, 伸悟 徳島大学
キーワード
Paraquat
diquat
medical cation exchange resin
primary treatment
saline addtion
資料タイプ
学術雑誌論文
抄録
The removal characteristics of paraquat and diquat by medical cation exchange resins (kayexalate and kalimate) for primary treatment of acute poisoning due to the accidental, suicidal or homicidal ingestion of herbicide were investigated in vitro.
The removed amounts of paraquat and diquat by kayexalate was larger than those by kalimate. And it was recognized that kayexalate is selective remover for paraquat and kalimate for diquat.
The inhibitory effect of sodium chloride addition on the paraquat and diquat removal by medical cation exchange resin was recognized. The degree of interference was proportional to the amount of sodium chloride added in the range of sodium chloride concentration up to 1.5%. The inhibitory effect of magnesium sulfide on the paraquat and diquat removal was also recognized. The degree of interference by saline addition onto kalimate was smaller compared with the case of kayexalate.
It is assumed that the difference of removal amount between paraquat and diquat by resins is due to the different strength of the polarity of paraquat and diquat. And it is assumed that the difference of removal effects between kayexalate and kalimate is due to the cation exchange capacity of resins.
The medical cation exchange resin is evaluated as the effective oral adsorbent, but it has to pay attention to the inhibitory effect of saline addition for the removal characteristics for paraquat and diquat by medical cation exchange resins from the standpoint of in vitro study.
掲載誌名
四国医学雑誌
ISSN
00373699
cat書誌ID
AN00102041
出版者
徳島医学会
52
1
開始ページ
14
終了ページ
23
並び順
14
発行日
1996-02-25
フルテキストファイル
言語
jpn
著者版フラグ
出版社版
部局
医学系