ID 111876
タイトル別表記
Facile Guanidine Formation under Mild Acidic Condition
著者
Takeuchi, Kohei Hokkaido University
Tanino, Keiji Hokkaido University
キーワード
guanidinylation
cyclic guanidine
isothiourea
bis(trifluoromethansulfonyl)imide
ammonium bis(trifluoromethansulfonyl)imidate
資料タイプ
学術雑誌論文
抄録
An efficient method for converting isothioureas into guanidines was developed. The use of amine salts of bis(trifluoromethanesulfonyl)imide as a nitrogen source was found to induce an efficient conversion under weak acidic condition at 50 °C. The conversion was applicable to the various amines and carbamate-protected thioureas, and various carbamate-protected cyclic guanidines were obtained in high yields. In particular, ammonium bis(trifluoromethanesulfonyl)imide salt is a useful N1 source with which to construct mono-protected cyclic guanidines.
掲載誌名
Synlett
ISSN
09365214
14372096
cat書誌ID
AA10731110
AA12357740
出版者
Thieme
27
18
開始ページ
2591
終了ページ
2596
発行日
2016-08-01
権利情報
© 2016 Georg Thieme Verlag Stuttgart · New York
EDB ID
329992
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
著者版
部局
薬学系