| ID | 111876 |
| タイトル別表記 | Facile Guanidine Formation under Mild Acidic Condition
|
| 著者 |
Takeuchi, Kohei
Hokkaido University
Tanino, Keiji
Hokkaido University
|
| キーワード | guanidinylation
cyclic guanidine
isothiourea
bis(trifluoromethansulfonyl)imide
ammonium bis(trifluoromethansulfonyl)imidate
|
| 資料タイプ |
学術雑誌論文
|
| 抄録 | An efficient method for converting isothioureas into guanidines was developed. The use of amine salts of bis(trifluoromethanesulfonyl)imide as a nitrogen source was found to induce an efficient conversion under weak acidic condition at 50 °C. The conversion was applicable to the various amines and carbamate-protected thioureas, and various carbamate-protected cyclic guanidines were obtained in high yields. In particular, ammonium bis(trifluoromethanesulfonyl)imide salt is a useful N1 source with which to construct mono-protected cyclic guanidines.
|
| 掲載誌名 |
Synlett
|
| ISSN | 09365214
14372096
|
| cat書誌ID | AA10731110
AA12357740
|
| 出版者 | Thieme
|
| 巻 | 27
|
| 号 | 18
|
| 開始ページ | 2591
|
| 終了ページ | 2596
|
| 発行日 | 2016-08-01
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| 権利情報 | © 2016 Georg Thieme Verlag Stuttgart · New York
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| EDB ID | |
| 出版社版DOI | |
| 出版社版URL | |
| フルテキストファイル | |
| 言語 |
eng
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| 著者版フラグ |
著者版
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| 部局 |
薬学系
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