ID | 111924 |
著者 |
Shimizu, Tatsuhiko
Tokushima University
Miyajima, Rin
Tokushima University
Sato, Kohei
Tokushima University
Sakamoto, Ken
Tokushima University
Naruse, Naoto
Tokushima University
Kita, Miku
Tokushima University
|
キーワード | C-Terminal peptide thioacids
N-Sulfanylethylanilide peptide
Hydrothiolysis
Phosphate buffer
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資料タイプ |
学術雑誌論文
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抄録 | A facile procedure has been developed for the synthesis of C-terminal peptide thioacids under mild conditions. A series of N-sulfanylethylanilide peptides prepared using Fmoc-based solid-phase peptide synthesis were successfully converted to the corresponding thioacids via a hydrothiolysis reaction in a phosphate buffer with only trace epimerization of the C-terminal amino acid.
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掲載誌名 |
Tetrahedron
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ISSN | 00404020
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cat書誌ID | AA00861787
AA11539786
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出版者 | Elsevier Ltd.
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巻 | 72
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号 | 7
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開始ページ | 992
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終了ページ | 998
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発行日 | 2015-12-29
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権利情報 | © 2015. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
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EDB ID | |
出版社版DOI | |
出版社版URL | |
フルテキストファイル | |
言語 |
eng
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著者版フラグ |
著者版
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部局 |
薬学系
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