ID 111937
著者
キーワード
Xerostomia
Aquaporin-5
Functional foods
Secretagogues
資料タイプ
学術雑誌論文
抄録
Xerostomia, or dry mouth, is mainly caused by systemic disease, biological aging, and drug-induced side effect. The innervations underlying the three major salivary glands and numerous minor salivary glands differ substantially. The trafficking of aquaporin-5 (AQP5), which is specifically expressed in salivary glands, is regulated by the autonomic nerves. Upon the stimulation of the cholinergic nerve, AQP5 travels to apical and lateral plasma membranes, nuclei, and saliva. In this review article, I will describe the subcellular localization of AQP5 in relation to the causes of xerostomia. Ways of managing xerostomia, in particular the use of functional foods and salivary secretagogues, are also discussed.
掲載誌名
Journal of Oral Health and Biosciences
ISSN
21896682
出版者
四国歯学会
31
1
開始ページ
49
終了ページ
56
並び順
49
発行日
2018-07-05
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
歯学系