直近一年間の累計
アクセス数 : ?
ダウンロード数 : ?
ID 112029
タイトル別表記
Auditory Evoked Potential (AEP) in Manic Depressive Illness (MDI)
躁うつ病患者の聴覚性誘発電位
著者
岡田, 健 徳島大学
吉松, 誠 徳島大学
大蔵, 雅夫 徳島大学
生田, 琢己 徳島大学
川端, 茂雄 徳島大学
キーワード
auditory evoked potentials
MDI
sexes
lithium
carbamazepine
資料タイプ
学術雑誌論文
抄録
The differences between MDI patients and healthy subjects in Auditory Evoked Potential (AEP) were studied with 45 MDI subjects (22 males and 23 females) and 60 healthy subjects (30 males and 30 females). AEPs were recorded through the two deviations (3 rd CH : Cz→A1+2 and 6 th CH : Cz→T5), together with EEG. The following results were obtained.
1. Almost of the peak latencies of AEP components were longer in MDI subjects than those in healthy ones, both in males and females. The interpeak amplitude N2-P3 and P4-N4 in both derivations were significantly larger in male patients. The predominant amplitude N4-P5 and P5-N5 in both derivations significantly small in females.
2. Furthermore, there were little significant differences between AEP recorded in manic and depressive condition of the patients.
3. There were little significant differences in AEP between the patients treated regularly with lithium or carbamazepine and not, and between who had the clinical history more than 2 years and not.
These results indicate some dysfunctions in reticular formation, thalamus, up to the primary and secondary auditory cortex in MDI. suggesting the single pathophysiological basis under laying manic-depressive illness.
掲載誌名
四国医学雑誌
ISSN
00373699
cat書誌ID
AN00102041
出版者
徳島医学会
54
1
開始ページ
63
終了ページ
74
並び順
63
発行日
1998-02-25
フルテキストファイル
言語
jpn
著者版フラグ
出版社版