ID | 115970 |
タイトル別表記 | リンパ節のPET/CTによるSUVmaxに重み付け係数を乗じてCECTの最大短径を加えた新しいcombined indexによる舌癌の臨床的N0症例の潜在的リンパ節転移の評価
Combined index to evaluate N0 neck
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著者 |
Suzuki, Motoyuki
Osaka International Cancer Institute|Osaka University
Otozai, Shinji
Osaka International Cancer Institute
Yoshii, Tadashi
Osaka International Cancer Institute
Okamoto, Hidehiko
International University of Health and Welfare
Fujii, Takashi
Tokushima University
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キーワード | Tongue cancer
lymph node metastasis
clinical N0 neck
occult nodal metastasis
PET/CT
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資料タイプ |
学位論文
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抄録 | To predict occult nodal metastasis in clinical N0 patients with tongue cancer, we developed combined index (CI) : SUVmax of the largest lymph node in PET/CT by weighting coefficient plus its maximum minor axis (< 10 mm) in contrast-enhanced CT (CECT). In this retrospective study, 57 clinical N0 patients with tongue cancer, who underwent elective supraomohyoid neck dissection at cervical levels of I-III were enrolled. The cutoff value of SUVmax of 2.0 obtained using receiver operating characteristic (ROC) analysis predicted the postoperative positive cervical levels containing metastatic lymph nodes from clinical N0 cervical levels in tongue cancer patients with a sensitivity of 54.5% and a specificity of 78.2%. The cutoff value of CI with weighting coefficient of 1.5 obtained using ROC analysis was 9.8 at the maximum area under the curve of 0.750. The cutoff value of 9.8 predicted the postoperative positive cervical levels containing metastatic lymph nodes from clinical N0 cervical levels in tongue cancer patients with a sensitivity of 68.2% and a specificity of 81.5%. These findings suggest that CI of functional PET/CT and morphological CECT components might improve the diagnostic performance of occult nodal metastasis to select clinical N0 patients with tongue cancer preferable for elective neck dissection.
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掲載誌名 |
The Journal of Medical Investigation
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ISSN | 13496867
13431420
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cat書誌ID | AA11166929
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出版者 | Tokushima University Faculty of Medicine
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巻 | 68
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号 | 1-2
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開始ページ | 154
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終了ページ | 158
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並び順 | 154
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発行日 | 2021-02
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備考 | 内容要旨・審査要旨・論文本文の公開
本論文は,著者Ryo Kanamuraの学位論文として提出され,学位審査・授与の対象となっている。 |
EDB ID | |
出版社版DOI | |
出版社版URL | |
フルテキストファイル | |
言語 |
eng
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著者版フラグ |
博士論文全文を含む
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文科省報告番号 | 甲第3487号
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学位記番号 | 甲医第1491号
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学位授与年月日 | 2021-03-17
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学位名 |
博士(医学)
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学位授与機関 |
徳島大学
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部局 |
医学系
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