ID 83944
著者
倉立, 真志 Department of Surgery, Tokushima Prefectural Central Hospital
イノウエ, セイヤ Department of Surgery, Tokushima Prefectural Central Hospital 徳島大学 教育研究者総覧
チカキヨ, モトヤ Department of Surgery, Tokushima Prefectural Central Hospital
カネダ, ユウジ Department of Surgery, Tokushima Prefectural Central Hospital
ハリノ, ユカリ Department of Surgery, Tokushima Prefectural Central Hospital
広瀬, 敏幸 Department of Surgery, Tokushima Prefectural Central Hospital
ヤギ, トシユキ Department of Surgery, Tokushima Prefectural Central Hospital
サイトウ, セイヤ Department of Surgery, Tokushima Prefectural Central Hospital
住友, 正幸 Department of Surgery, Tokushima Prefectural Central Hospital
フジノ, リョウゾウ Department of Surgery, Tokushima Prefectural Central Hospital
サタケ, ノブオ Department of Human Pathology, Tokushima Prefectural Central Hospital
キーワード
neuroendocrine cell carcinoma
rectum
adenoendocrine cell carcinoma
small cell carcinoma
資料タイプ
学術雑誌論文
抄録
A 74-years old man was referred to our hospital for treatment of a rectal mass.
Colonoscopy revealed villous tumor covering all the lower rectal lumen. Biopsy yielded
a diagnosis of adenoma. CT examination showed tumor shadows of the rectum and the
liver. Pelvic MRI examination showed a 10.5 8 7 cm tumor with high signal intensity on
the T2 weighted images in the rectum. Rectosigmoidectomy with lymph node dissection
was performed with the diagnosis of rectal cancer that metastasized to the liver. Histological
and immuno- histochemical features showed coexistent poorly-differentiated small
cell neuroendocrine cell (NEC) carcinoma and non-invasive well-differentiated adenocarcinoma
in tubulovillous adenoma. However the chemotherapy with FOLFOX and
Bevacizumab was performed postoperatively, the patient died in cancer 3 months after
surgery. Rectal poorly-differentiated NEC carcinomas are thought to be a tumor with a
high malignant potential. Recently, the UICC TNM classifications of malignant tumors,
7th edition and the Guidelines for colorectal NEC tumors of European Neuroendocrine
Tumor Society have been published. They would be evaluated, and effective multimodal
therapy for NEC carcinomas should be established.
掲載誌名
The journal of medical investigation : JMI
ISSN
13431420
cat書誌ID
AA11166929
57
3-4
開始ページ
338
終了ページ
344
並び順
338
発行日
2010-08
備考
The journal of medical investigation : http://medical.med.tokushima-u.ac.jp/jmi/index.html
フルテキストファイル
言語
eng
部局
医学系