ID | 115450 |
タイトル別表記 | Chemotherapy on QOL and night sleep of CC patients
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著者 |
Okitsu, Hiroshi
Tokushima Red Cross Hospital
Miyake, Hidenori
Tokushima Municipal Hospital
Yagi, Toshiyuki
Tokushima Prefectural Central Hospital
Miura, Murato
Yoshinogawa Medical center
Bando, Yoshiaki
Tokushima Prefectural Naruto Hospital
Ando, Tsutomu
Tokushima Prefectural Miyoshi Hospital
Hotchi, Masanori
Ehime Prefectural Central Hospital
Ishikawa, Masashi
Shikoku Central Hospital
Fukuyama, Mitsutoshi
Kochi National Hospital
Wada, Daisuke
Takamatsu Municipal Hospital
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キーワード | Chemotherapy
QOL
Sleep disturbance
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資料タイプ |
学術雑誌論文
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抄録 | Background : The aim of this study was to investigate quality of life (QOL) and night-time sleep disturbance in colon cancer patients with middle risk chemotherapy for proper antiemetic therapy. Methods : The study enrolled 139 patients with colorectal cancer. All patients received oxaliplatin or irinotecan-based chemotherapy. Patients completed a questionnaire about chemotherapy-induced nausea and vomiting and sleep disturbance. Sleep disturbance was checked, and the relationship between sleep disturbance and nausea was analyzed. Results : The prevalence of nausea was 48.9% (68 / 139). The degree of the nausea was slight / moderate / severe in 51 / 11 / 6 patients, and 12 patients had vomiting. Appetite showed no change / slightly decreased / half / one-fourth / none in 51 / 34 / 33 / 6 / 7 patients. There were significant differences in the mental component summary (MCS) score and the role-social component score (RCS). (MCS : nausea(+) vs nausea(-) 46.4 ± 1.1 vs 54.1 ± 1.1 p < 0.01 RCS : nausea(+) vs nausea(-) 33.1 ± 2.1 vs 41.6 ± 2.1 p < 0.01). Using the MCS with a cut-off score of 50, patients were divided into two groups, and nausea was significantly correlated with a low MCS score. Furthermore, patients were divided into two groups using a Pittsburgh Sleep Quality Index cut-off score of 6, and sleep disturbance was correlated with old age and second-line chemotherapy. Conclusions : Nausea affects QOL and night-time sleep of colon cancer patients with middle risk chemotherapy.
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掲載誌名 |
The Journal of Medical Investigation
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ISSN | 13496867
13431420
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cat書誌ID | AA11166929
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出版者 | Tokushima University Faculty of Medicine
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巻 | 67
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号 | 3-4
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開始ページ | 338
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終了ページ | 342
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並び順 | 338
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発行日 | 2020-08
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出版社版DOI | |
出版社版URL | |
フルテキストファイル | |
言語 |
eng
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著者版フラグ |
出版社版
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部局 |
病院
医学系
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