アクセス数 : ?
ダウンロード数 : ?
ID 115450
タイトル別表記
Chemotherapy on QOL and night sleep of CC patients
著者
Okitsu, Hiroshi Tokushima Red Cross Hospital
Miyake, Hidenori Tokushima Municipal Hospital
Yagi, Toshiyuki Tokushima Prefectural Central Hospital
Miura, Murato Yoshinogawa Medical center
Bando, Yoshiaki Tokushima Prefectural Naruto Hospital
Ando, Tsutomu Tokushima Prefectural Miyoshi Hospital
Hotchi, Masanori Ehime Prefectural Central Hospital
Ishikawa, Masashi Shikoku Central Hospital
Fukuyama, Mitsutoshi Kochi National Hospital
Wada, Daisuke Takamatsu Municipal Hospital
キーワード
Chemotherapy
QOL
Sleep disturbance
資料タイプ
学術雑誌論文
抄録
Background : The aim of this study was to investigate quality of life (QOL) and night-time sleep disturbance in colon cancer patients with middle risk chemotherapy for proper antiemetic therapy. Methods : The study enrolled 139 patients with colorectal cancer. All patients received oxaliplatin or irinotecan-based chemotherapy. Patients completed a questionnaire about chemotherapy-induced nausea and vomiting and sleep disturbance. Sleep disturbance was checked, and the relationship between sleep disturbance and nausea was analyzed. Results : The prevalence of nausea was 48.9% (68 / 139). The degree of the nausea was slight / moderate / severe in 51 / 11 / 6 patients, and 12 patients had vomiting. Appetite showed no change / slightly decreased / half / one-fourth / none in 51 / 34 / 33 / 6 / 7 patients. There were significant differences in the mental component summary (MCS) score and the role-social component score (RCS). (MCS : nausea(+) vs nausea(-) 46.4 ± 1.1 vs 54.1 ± 1.1 p < 0.01 RCS : nausea(+) vs nausea(-) 33.1 ± 2.1 vs 41.6 ± 2.1 p < 0.01). Using the MCS with a cut-off score of 50, patients were divided into two groups, and nausea was significantly correlated with a low MCS score. Furthermore, patients were divided into two groups using a Pittsburgh Sleep Quality Index cut-off score of 6, and sleep disturbance was correlated with old age and second-line chemotherapy. Conclusions : Nausea affects QOL and night-time sleep of colon cancer patients with middle risk chemotherapy.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA11166929
出版者
Tokushima University Faculty of Medicine
67
3-4
開始ページ
338
終了ページ
342
並び順
338
発行日
2020-08
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
病院
医学系