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ID 112328
タイトル別表記
Exercise on the Structure and Circulation of Choroid
著者
木下, 貴正 Tokushima University|Sapporo City General Hospital
Mori, Junya Sapporo City General Hospital
Okuda, Natsuki Sapporo City General Hospital
Imaizumi, Hiroko Sapporo City General Hospital
Iwasaki, Masanori Sapporo City General Hospital
Shimizu, Miho Sapporo City General Hospital
Miyamoto, Hirotomo Sapporo City General Hospital
Akaiwa, Kei Tokushima University
Sonoda, Shozo Kagoshima University
Sakamoto, Taiji Kagoshima University
資料タイプ
学術雑誌論文
抄録
Aims
To determine the effects of dynamic exercise on the circulation and the luminal and stromal areas of the choroid in normal eyes.

Methods
This was a prospective interventional study of 38 eyes of 38 normal subjects enrolled by invitation. The systolic and diastolic blood pressures, heart rate, intraocularpressure, mean ocular perfusion pressure (MOPP), choroidal blood velocity, and enhanced depth imaging optical coherence tomographic (EDI-OCT) images were recorded before, and immediately after mild dynamic exercise. The same measurements were recorded after 10 min of rest. The choroidal blood velocity was measured bylaser speckle flowgraphy, and the mean blur rate was used for the evaluations. The horizontal EDI-OCT images of the subfoveal choroid were converted to binary images. The central choroidal thickness (CCT), total cross sectional choroidal area, luminal areas, stromal areas, and the ratio of luminal area to total choroidal area (L/C ratio) were determined from these images.

Results
The systolic and diastolic blood pressures, heart rate, MOPP, and the mean blur rate were significantly increased immediately after the exercise and significantly decreased 10 minutes after the exercise. There wereno significant changes in the mean CCT, the mean total choroidal area, the mean luminal and stromal areas, and the mean L/C ratio after the exercise.

Conclusions
Our results suggest that a rest period is needed before measurements of blood flow velocity but not necessary for the EDI-OCT imaging to determine the choroidal thickness and area.
掲載誌名
PLOS ONE
ISSN
19326203
出版者
PLOS
11
12
開始ページ
e0168336
発行日
2016-12-14
権利情報
Copyright: © 2016 Kinoshita et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
病院
医学系