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ID 109381
タイトル別表記
さまざまな身体活動レベルにおけるヒトの骨格筋量と筋力に対する食事性大豆たんぱく質の効果
Effect of soy protein on the muscle in human
著者
橋本, 理恵 徳島大学大学院栄養生命科学教育部(人間栄養科学専攻)
Sakai, Atsuko The University of Tokushima
Murayama, Masumi The University of Tokushima
Ochi, Arisa The University of Tokushima
安倍, 知紀 The University of Tokushima KAKEN研究者をさがす
平坂, 勝也 The University of Tokushima|Nagasaki University KAKEN研究者をさがす
Ohno, Ayako The University of Tokushima
Inatsugi, Mikiko Inatsugi Orthopedic Hospital
Doi, Daisuke Inatsugi Orthopedic Hospital
Takeda, Masanori Kyoritsu Hospital
キーワード
bedridden patients
casein
muscle volume
quadriceps femoris muscle
soy protein isolate
資料タイプ
学位論文
抄録
Background : In recent years, the number of bedridden people is rapidly increasing due to aging or lack of exercise in Japan. This problem is becoming more serious, since there is no countermeasure against it. In the present study, we designed to investigate whether dietary proteins, especially soy, had beneficial effects on skeletal muscle in 59 volunteers with various physical activities. Methods : We subjected 59 volunteers with various physical activities to meal intervention examination. Persons with low and high physical activities were divided into two dietary groups, the casein diet group and the soy diet group. They ate daily meals supplemented with 7.8 g of powdered casein or soy protein isolate every day for 30 days. Bedridden patients in hospitals were further divided into three dietary groups : the no supplementation diet group, the casein diet group and the soy diet group. They were also subjected to a blood test, a urinalysis, magnetic resonance imaging analysis and muscle strength test of the knee before and after the meal intervention study. Results : Thirty-day soy protein supplementation significantly increased skeletal muscle volume in participants with low physical activity, compared with 30-day casein protein supplementation. Both casein and soy protein supplementation increased the volume of quadriceps femoris muscle in bedridden patients. Consistently, soy protein significantly increased their extension power of the knee, compared with casein protein. Although casein protein increased skeletal muscle volume more than soy protein in bedridden patients, their muscle strength changes by soy protein supplementation were bigger than those by casein protein supplementation. Conclusions : The supplementation of soy protein would be one of the effective foods which prevent the skeletal muscle atrophy caused by immobilization or unloading.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA12022913
AA11166929
出版者
Tokushima University Faculty of Medicine
62
3-4
開始ページ
177
終了ページ
183
並び順
177
発行日
2015-08
備考
内容要旨・審査要旨・論文本文の公開:
内容要旨・審査要旨 : LID201505251027.pdf
論文本文 : k2851_fulltext.pdf
本論文は,著者Rie Hashimotoの学位論文として提出され, 学位審査・授与の対象となっている。
著者の申請により要約(2015-05-26公開)に替えて論文全文を公開(2020-04-10)
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
博士論文全文を含む
文科省報告番号
甲第2851号
学位記番号
甲栄第229号
学位授与年月日
2015-03-26
学位名
博士(栄養学)
学位授与機関
徳島大学
部局
医学系
病院
生物資源系