ID 110704
著者
藤井, 正彦 Department of Digestive Pediatric Surgery, The University of Tokushima School of Medicine
三宅, 秀則 Department of Digestive Pediatric Surgery, The University of Tokushima School of Medicine
ササキ, カツヤ Department of Digestive Pediatric Surgery, The University of Tokushima School of Medicine
高木, 敏秀 Department of Digestive Pediatric Surgery, The University of Tokushima School of Medicine
タカムラ, カズヒト Department of Digestive Pediatric Surgery, The University of Tokushima School of Medicine
田代, 征記 Department of Digestive Pediatric Surgery, The University of Tokushima School of Medicine 徳島大学 教育研究者総覧
キーワード
pancreatic carcinoma
arterial infusion chemotherapy
liver metastases
資料タイプ
学術雑誌論文
抄録
Introduction : Despite various treatment trials for unresectable pancreatic carcinoma with liver metastases, the outcome has not been satisfactory. This paper reports a case of pancreatic carcinoma with multiple liver metastases that responded well to arterial infusion chemotherapy. Case report : A 65-year-old male was diagnosed with multiple liver tumors, and needle biopsy revealed adenocarcinoma. With endoscopic ultrasonography, a tumor in the pancreatic head was detected, and pancreatic carcinoma with multiple liver metastases was diagnosed. He received arterial infusion chemotherapy : cisplatin at a dose of 10mg/body/day and 500mg/body/day of 5-fluorouracil. After 14 days administration, liver metastases had decreased in number and size, but thereafter, because of hepatic arterial occlusion, the same dose of drugs was administered intravenously. The patient was discharged from the hospital and was given chemotherapy 3 days a week on an outpatient basis. Although the chemotherapy was effective, it was stopped because of severe general fatigue 5months after discharge. His general status continued to gradually worsen,and he died 12 months after diagnosis. Conclusions : Prognosis of pancreatic carcinoma with liver metastases is poor however, transarterial infusion chemotherapy may be effective to improve the prognosis and quality of life of the patients.
掲載誌名
The journal of medical investigation : JMI
ISSN
13431420
cat書誌ID
AA11166929
50
3-4
開始ページ
199
終了ページ
202
並び順
199
発行日
2003
EDB ID
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系