| ID | 117574 |
| 著者 |
Takechi, Nao
Tokushima University
Yamanomoto, Ken
Tokushima University
|
| キーワード | Flavin
Peptide
Aerobic oxidation
DFT calculation
|
| 資料タイプ |
学術雑誌論文
|
| 抄録 | The original flavopeptide catalyst, 3-FlC2-L-Pro-L-Tyr-L-Asp-Ado-NH-PS (Fl-PepLLL), and its diastereomers including Fl-PepDDL, Fl-PepLDL, and Fl-PepDLL were synthesized to investigate the correlation between their catalytic activity and stereochemistry. The results and related computations showed the importance of intramolecular hydrogen bonds involving the Asp residue in their 4a-hydroperoxy forms for the catalysis.
|
| 掲載誌名 |
Tetrahedron Letters
|
| ISSN | 00404039
|
| cat書誌ID | AA00861801
AA11539822
|
| 出版者 | Elsevier
|
| 巻 | 73
|
| 開始ページ | 153107
|
| 発行日 | 2021-04-22
|
| 権利情報 | © 2021. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
|
| EDB ID | |
| 出版社版DOI | |
| 出版社版URL | |
| フルテキストファイル | |
| 言語 |
eng
|
| 著者版フラグ |
著者版
|
| 部局 |
理工学系
教養教育院
|
