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ID 115492
タイトル別表記
Enantiomer-selective Anti-influenza Activity of Bakuchiol
著者
Shoji, Masaki Tokushima Bunri University
Arakaki, Yumie Tokushima Bunri University
Esumi, Tomoyuki Tokushima Bunri University
Kohnomi, Shuntaro Tokushima Bunri University
Yamamoto, Chihiro Tokushima Bunri University
Suzuki, Yutaka University of Tokyo
Konishi, Shiro Tokushima Bunri University
Kuzuhara, Takashi Tokushima Bunri University
資料タイプ
学術雑誌論文
抄録
Background: Novel therapeutic approaches against influenza are required. Bakuchiol is a phenolic isoprenoid found in Babchi seeds.
Results: Bakuchiol enantiomer-selectively inhibited influenza A viral infection and growth and activated the Nrf2 pathway.
Conclusion: Bakuchiol showed novel enantiomer-selective anti-influenza viral activity.
Significance: The study of bakuchiol will contribute to the development of novel approaches to influenza therapy.
掲載誌名
Journal of Biological Chemistry
ISSN
00219258
cat書誌ID
AA1202441X
出版者
The American Society for Biochemistry and Molecular Biology
290
46
開始ページ
28001
終了ページ
28017
発行日
2015-10-07
権利情報
Final version free via Creative Commons CC-BY license(https://creativecommons.org/licenses/by/4.0/).
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
先端酵素学研究所