| ID | 117254 |
| 著者 | |
| キーワード | Multiple myeloma (Plasma cell myeloma)
Bone diseases
Osteoclasts
Osteoblasts
Osteocytes
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| 資料タイプ |
学術雑誌論文
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| 抄録 | Multiple myeloma (Plasma cell myeloma), a malignancy of the plasma cells, exhibits tumor expansion preferentially in the bone marrow and the development of bone-destructive lesions. Multiple myeloma is still an incurable disease with changes in the bone marrow microenvironment in favor of the survival and proliferation of multiple myeloma cells and bone destruction. In this review, we described the recent findings on the regulators involved in the development of myeloma bone diseases, and succinctly summarize currently available therapeutic options and the development of novel bone modifying agents for myeloma treatment.
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| 掲載誌名 |
Japanese Dental Science Review
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| ISSN | 18827616
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| cat書誌ID | AA12334461
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| 出版者 | Japanese Association for Dental Science|Elsevier
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| 巻 | 57
|
| 開始ページ | 164
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| 終了ページ | 173
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| 発行日 | 2021-09-23
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| 権利情報 | This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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| EDB ID | |
| 出版社版DOI | |
| 出版社版URL | |
| フルテキストファイル | |
| 言語 |
eng
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| 著者版フラグ |
出版社版
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| 部局 |
歯学系
病院
医学系
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