アクセス数 : ?
ダウンロード数 : ?
ID 114034
タイトル別表記
Definite ECRS diagnosis with systemic steroid
著者
藤本, 知佐 Yoshinogawa Medical Center|Tokushima Municipal Hospital
田村, 公一 Tokushima Municipal Hospital KAKEN研究者をさがす
Takaishi, Shizuka Tokushima Municipal Hospital
Kawata, Ikuji Yoshinogawa Medical Center
キーワード
eosinophilic chronic rhinosinusitis (ECRS)
chronic rhinosinusitis with nasal polyps
preoperative systemic steroids
endoscopic sinus surgery (ESS)
Japanese Epidemiological Survey of Refractory Eosinophilic Chronic Rhinosinusitis (JESREC)
資料タイプ
学術雑誌論文
抄録
According to JESREC criteria, definite eosinophilic chronic rhinosinusitis (ECRS) is postoperatively diagnosed based on over 70 eosinophils in high power magnification fields of the resected nasal polyps in patients with probable ECRS. Preoperative systemic administration with steroid is a standard practice, because it reduced intraoperative bleeding during endoscopic sinus surgery (ESS) in patients with ECRS. However, it was recently reported that systemic administration with steroid decreased the number of eosinophils in the nasal polyps, leading to a false negative diagnosis of definite ECRS. To overcome the risk, we have adopted short-term pre-operative systemic administration with low-dose of steroid and examined if our steroid administration makes a false-negative diagnosis. We performed a retrospective chart review of 42 patients with probable ECRS. Eleven patients were administered with 0.5 mg of bethametasone for 7 days before ESS, and other 31 patients were not administered. The average number of eosinophils in nasal polyps in patients who were administered with steroid was 188 ± 167, which was not different from 199 ± 149 in the patients who were not administered. These findings suggest that short-term preoperative administration with low-dose of steroid has few risk of a false-negative diagnosis of definite ECRS.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA12022913
AA11166929
出版者
Tokushima University Faculty of Medicine
66
3-4
開始ページ
233
終了ページ
236
並び順
233
発行日
2019-08
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
病院
医学系