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ID 117254
著者
キーワード
Multiple myeloma (Plasma cell myeloma)
Bone diseases
Osteoclasts
Osteoblasts
Osteocytes
資料タイプ
学術雑誌論文
抄録
Multiple myeloma (Plasma cell myeloma), a malignancy of the plasma cells, exhibits tumor expansion preferentially in the bone marrow and the development of bone-destructive lesions. Multiple myeloma is still an incurable disease with changes in the bone marrow microenvironment in favor of the survival and proliferation of multiple myeloma cells and bone destruction. In this review, we described the recent findings on the regulators involved in the development of myeloma bone diseases, and succinctly summarize currently available therapeutic options and the development of novel bone modifying agents for myeloma treatment.
掲載誌名
Japanese Dental Science Review
ISSN
18827616
cat書誌ID
AA12334461
出版者
Japanese Association for Dental Science|Elsevier
57
開始ページ
164
終了ページ
173
発行日
2021-09-23
権利情報
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
歯学系
病院
医学系