直近一年間の累計
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ID 115079
タイトル別表記
Regeneration of complex oral organs
Cell differentiation and development
著者
大島, 正充 Tokushima University|RIKEN Center for Developmental Biology 徳島大学 教育研究者総覧 KAKEN研究者をさがす
Ogawa, Miho RIKEN Center for Developmental Biology|Organ Technologies
Tsuji, Takashi RIKEN Center for Developmental Biology|Organ Technologies
資料タイプ
学術雑誌論文
抄録
The development of organoid techniques for regenerative therapy has progressed remarkably with the use of tissue-derived stem cells and pluripotent stem cells based on stem cell biology and tissue engineering technology. To realize whole-organ replacement therapy as next-generation regenerative medicine, it is expected that fully functional bioengineered organs can be reconstructed using an in vitro three-dimensional (3D) bioengineered organ germ and organoids by stem cell manipulation and self-organization. In this mini-review, we focused on substantial advances of 3D bioengineering technologies for the regeneration of complex oral organs with the reconstruction of 3D bioengineered organ germ using organ-inductive potential embryo-derived epithelial and mesenchymal cells. These bioengineering technologies have the potential for realization of future organ replacement therapy.
掲載誌名
Current Opinion in Cell Biology
ISSN
09550674
cat書誌ID
AA10753496
AA11524927
出版者
Elsevier
49
開始ページ
84
終了ページ
90
発行日
2017-12-28
権利情報
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
歯学系