IVRを用いた肝癌に対する局所治療

Local medical treatment, primarily using subsegmental TAE, was attempted as the initial treatment for overt HCC. Local responses, local tumor recurrence and survival rates were analyzed for 56 patients who underwent this treatment after 1991. Of the 56 patients, 51 (91 %) showed satisfactory local responses to the therapy. For 4 patients (8%), tumor recurred locally during the approximately 22 months follow up period, although the diagnostic images taken soon after treatment had suggested adequate local responses. Multiple tumor recurrence was found in 19 cases (34%). Seventeen patients were retreated. The cumulative survival rate was 89% after one year, 70% after 3 years, 47% after 5 years and 23% after 8 years. Considering that the subjects of this study included patients with poor hepatic reserves and patients with extensive HCC, the results of this therapy can be deemed to be comparable or superior to the outcome of surgical treatment. Therefore local therapy using IVR is expected to be useful for treating HCC.