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ID 110155
著者
Session, Adam M
ウノ, ヨシノブ
Kwon, Taejoon
Chapman, Jarrod A.
トヨダ, アツシ
タカハシ, シュウジ
フクイ, アキマサ
ヒコサカ, アキラ
スズキ, アツシ
コンドウ, マリコ
Heeringen, Simon J. van
Quigley, Ian
Heinz, Sven
オギノ, ハジメ
オチ, ハルキ
Hellsten, Uffe
Lyons, Jessica B.
Simakov, Oleg
Putnam, Nicholas
Stites, Jonathan
クロキ, ヨウコ
タナカ, トシアキ
ミチウエ, タツオ
渡部, 稔 Institute of Institution of Liberal Arts and Fundamental Education, Tokushima University 徳島大学 教育研究者総覧 KAKEN研究者をさがす
Bogdanovic, Ozren
Lister, Ryan
Georgiou, Georgios
Paranjpe, Sarita S.
Kruijsbergen, Ila van
Shu, Shengquiang
Carlson, Joseph
キノシタ, ツトム
オオタ, ユウコ
マワリブチ, シュウジ
Jenkins, Jerry
Grimwood, Jane
Schmutz, Jeremy
Mitros, Therese
Mozaffari, Sahar V.
スズキ, ユタカ
ハラモト, ヨシカズ
ヤマモト, タカマサ
タカギ, チヨ
Heald, Rebecca
Miller, Kelly
Haudenschild, Christian
Kitzman, Jacob
ナカヤマ, タクヤ
イズツ, ユミ
Robert, Jacques
Fortriede, Joshua
Burns, Kevin
Lotay, Vaneet
Karimi, Kamran
ヤスオカ, ユウリ
Dichmann, Darwin S.
Flajnik, Martin F.
Houston, Douglas W.
Shendure, Jay
DuPasquier, Louis
Vize, Peter D.
Zorn, Aaron M.
イトウ, ミチヒコ
Marcotte, Edward M.
Wallingford, John B.
イトウ, ユズル
アサシマ, マコト
ウエノ, ナオト
マツダ, ヨウイチ
Veenstra, Gert Jan C.
フジヤマ, アサオ
Harland, Richard M.
タイラ, マサノリ
Rokhsar, Daniel S.
資料タイプ
学術雑誌論文
抄録
To explore the origins and consequences of tetraploidy in the African clawed frog, we sequenced the Xenopus laevis genome and compared it to the related diploid X. tropicalis genome. We characterize the allotetraploid origin of X. laevis by partitioning its genome into two homoeologous subgenomes, marked by distinct families of ‘fossil’ transposable elements. On the basis of the activity of these elements and the age of hundreds of unitary pseudogenes, we estimate that the two diploid progenitor species diverged around 34 million years ago (Ma) and combined to form an allotetraploid around 17–18 Ma. More than 56% of all genes were retained in two homoeologous copies. Protein function, gene expression, and the amount of conserved flanking sequence all correlate with retention rates. The subgenomes have evolved asymmetrically, with one chromosome set more often preserving the ancestral state and the other experiencing more gene loss, deletion, rearrangement, and reduced gene expression.
掲載誌名
Nature
ISSN
00280836
14764687
cat書誌ID
AA11726193
538
開始ページ
336
終了ページ
343
並び順
336
発行日
2016-10-20
備考
Copyright © 2016 This work is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) licence. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons licence, users will need to obtain permission from the licence holder to reproduce the material. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
EDB ID
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
教養教育院